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    Arrow The Thyroid Paradox


    The Thyroid Paradox
    By James K. Rone M.D.



    Om boken...
    Dr. James K. Rone M.D. Homepage

    About the Author: James K. Rone, M.D., is a writer and private-practice endocrinologist in Murfreesboro, Tennessee. He is a former military physician, a member of the American Thyroid Association and the Endocrine Society and has been awarded fellowship in both the American College of Physicians and the American College of Endocrinology. Thyroid disease - in particular hypothyroidism - has been his focus of clinical interest for nearly twenty years, and he is a thyroid patient himself, giving him a unique empathy for those struggling with thyroid disorders. He lives with his wife Susan on their farm outside Nashville.


    CONTENTS

    • Introduction
    - Hypothyroidism is underdiagnosed
    - My Experience as Both, Physician and Patient
    - Irreconcilable Differences
    - Specialist Versus Generalist
    - Mainstreamist Versus Reformist
    - Origins of What We Know or Think We Know
    - Cookbook Medicine
    - An Open-Minded Approach

    • Acknowledgments

    CHAPTER 1
    • Thyroid Boot Camp
    - Thyroid Anatomy and Physiology
    - Thyroid Hormones
    - Why Is Thyroid Important?
    - Control of the Thyroid System

    CHAPTER 2
    • When to Think Low Thyroid
    - The Zulewski List
    - Fatigue
    - Weight Gain
    - Other Clues to Hypothyroidism
    - Who Needs Thyroid Testing?
    - My Criteria for Thyroid Testing

    CHAPTER 3
    • Low-Thyroid Diagnosis
    - Radiology
    - Basal Body Temperature
    - Tribute to a Forgotten Pioneer
    - Thyroid Blood Tests
    - Thyrotropin og Thyroid-Stimulating Hormone (TSH) Test
    - Normal and Abnormal TSH Levels
    - The Problem of Central Hypothyroidism
    - Free Thyroxine / Free T4 Test
    - Total Thyroxine / Total T4 Test
    - T3-Resin Uptake
    - Free Thyroxine Index
    - Total and Free Triiodothyronine (T3)
    - Thyroid Antibody Testing
    - TRH Stimulation Test
    - Current Mainstream Standards

    CHAPTER 4
    • Human Error in Thyroid Testing
    - Six Common Blunders
    - History of Exam Ignored in Favor of Test Results
    - TSH Test Is Not Done
    - Failure to Treat a High TSH Simply Because T4 or T3 Test Are Normal
    - Blowing Off a TSH of 5.0-10.0 mU/L as Insignificant or Not Warranting Therapy
    - Failure to Retest Borderline Results
    - Failure to Consider Central Hypothyroidism
    - Failure og Interpretation
    - Is It Always Normal to Be Normal?
    - Shades of Normal
    - The Individual versus the Population
    - Statistically versus Physiologically Normal
    - Redefining Normal TSH
    - How Much Hypothyroidism Is Missed
    - What's the Solution?

    CHAPTER 5
    • Atypical Hypothyroidism: Central Defects
    - Murphy's Law of the Thyroid
    - Points 1 and 2 - Brain and Pituitary Problems
    - Occult Central Hypothyroidism (OCH)
    - Post-Hyerthyroid OCH (Occult Central Hypothyroidism)
    - Jessica's Fall into Thyroid Purgatory
    - Steroid-Induced OCH (Occult Central Hypothyroidism)
    - Stress, Depression, and Steroids
    - The Stress-Steroid Connection

    CHAPTER 6
    • Atypical Hypothyroidism: Peripheral Defects
    - Point 3 - Making and Secreting T4 and T3
    - Point 4 - Transport Proteins
    - Points 5 and 7 - Entry of T4 and T3 Into Cells and Cell Nuclei
    - Point 6 - Conversion of T4 to T3
    - Point 8 and 9 - Thyroid Hormone Receptors
    - Hormone Resistance
    - Thyroid Hormone Resistance
    - Central versus Peripherial RTH (Resistance to Thyroid Hormones)
    - Point 10 - The Balancing Act

    CHAPTER 7
    • Thyroid Replacement 101
    - Branded versus Generic Drugs
    - Synthetic versus Natural
    - T4 versus T3
    - The Pros and Cons of Differing Thyroid Replacement Strategies
    - T4 Only
    - T3 Only
    - T4 / T3 Cocktail
    - Basic of Thyroid Replacement Therapy
    - A Field Guide to Thyroid Pills
    - How to take It
    - Monkey Wrenches
    - Thyroid Replacement and the Heart
    - Duration of Thyroid Replacement Therapy
    - Cost of Thyroid Replacement Therapy

    CHAPTER 8
    • Monitoring and Troubleshooting Thyroid Replacement
    - TSH Testing
    - The Problem of Low TSH
    - Testing Frequency
    - Full Replacement or Less?
    - When Good Labs Lie
    - Thyroid Replacement After Hyperthyroidism
    - Wright
    - Post-Hyperthyroid Central Hypothyroidism
    - Persistent TSIs (antibodies called thyroid-stimulating immuniglobulins)
    - Adverse Effects of Thyroid Replacement
    - Overdosing
    - Hyperthyroidism
    - HPT (hypothalamic–pituitary–thyroid) Axix Suppression
    - Unmasking
    - Troubleshooting Thyroid Replacement
    - Recipe for Succes
    - Starting Therapy
    - Monitoring and Adjusting Therapy
    - Follow-up

    CHAPTER 9
    • Escaping the Paradox
    - Cooking Soufflès in an Easy-Bake Oven
    - Why Evidence-Based Medicne?
    - Time
    - Knowledge
    - Cost
    - Physician Extenders
    - You Can Escape the Paradox
    - Conclusion

    • Epilogue
    • Glossary
    • References
    • Index
    • About the Author
    Til alle norske og danske stoffskifte-pasienter, anbefaler vi boken STOP stofskiftevanviddet, skrevet av verdens ledende pasient-aktivist Janie Bowthorpe, som i 2005 grunnla nettstedet Stop The Thyroid Madness. Boken er utgitt på dansk i 2014. För alla svenska hypotyreos-patienter, rekommenderar vi samma bok, översatt till svenska med titeln Stoppa sköldkörtelskandalen (2012). Til alle gode leger, og pasienter som ønsker å lære mer av "the right stuff", anbefaler vi boken Stop The Thyroid Madness II (2014) med bidrag fra 10 leger MD. I Skandinavia, definitivt de to beste og mest nyttige bøker for hypotyreose-pasienter, for deres familier og venner, og for deres leger.

  2. #2
    Medlem siden
    Mar 2009
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    Standard Sv: The Thyroid Paradox

    Til alle norske og danske stoffskifte-pasienter, anbefaler vi boken STOP stofskiftevanviddet, skrevet av verdens ledende pasient-aktivist Janie Bowthorpe, som i 2005 grunnla nettstedet Stop The Thyroid Madness. Boken er utgitt på dansk i 2014. För alla svenska hypotyreos-patienter, rekommenderar vi samma bok, översatt till svenska med titeln Stoppa sköldkörtelskandalen (2012). Til alle gode leger, og pasienter som ønsker å lære mer av "the right stuff", anbefaler vi boken Stop The Thyroid Madness II (2014) med bidrag fra 10 leger MD. I Skandinavia, definitivt de to beste og mest nyttige bøker for hypotyreose-pasienter, for deres familier og venner, og for deres leger.

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