Sitat Opprinnelig skrevet av Vigdis Vis post
Nora, så fint at du nevner Florinef. Det skal jeg si til legen min (han med små englevinger). Jeg forer legen min med lesestof, han sier jo at han leser seg opp på emnet, så jeg får finne noen sider om Florinef til ham. Men jeg tror det står noe om det i Safe uses of cortisol, som jeg lånte ham...
Ikke så meget om Florinef, men nævnt er det et par steder i bogen...:

Side 34:

Because patients with spontaneous adrenocortical deficiency usually seek medical care before a complete lack of cortisol develops, replacement dosages for such patients usually total less than 35 mg (hydrocortison/red.) daily, taken as 7,5, 5, or 2,5 mg four times daily before meals and at bedtime (ac and hs). Supplementary sodium-retaining effect the form of 9-alpha-fluorohydrocortisone (9-alpha-FF marketed as Florinef), 0,1 mg daily og three times weekly, is rarely needed exept in totally adrenalectomized patients.

Side 42:

Patients who have been totally adrenalectomized or who have more severe degrees of adrenocortical deficiency can usually be satisfactorily maintained on cortisol in a dosage of 10 mg at breakfast and lunch, 5 mg at supper, and 10 mg ad bedtime. Supplementary sodium-retaining activity may be necessary, and 9-alpha-fluorohydrocortisone (9-alpha-FF, marketed as Florinef), 0,05 to 0,1 mg daily or three times weeklyis sufficient in most cases.

Side 43:

In addition to supplementary sodium-retaining activity as provided by small doses of 9-alpha-fluorohydrocortisone (9-alpha-FF, marketed as Florinef), women with severe adrenal insufficiency may require supplementary androgen to achieve optimum strength and sense of well-being. This is not surprising since their chief source of androgen is normalIy their adrenals. Unfortunately, natural adrenal androgens such as dehydroepiandrosterone (DHEA) and androstenedione are not generally available for clinical use, but some pharmacists have 5 mg capsules of DHEA. Otherwise, 5 mg linguets of methyl testosterone may be helpful to provide androgenic effects. As will be discussed later, there is evidence that DHEA is a better replacement androgen for adrenal deficiency than testosterone. Women's International Pharmacy in Madison, Wisconsin is an excellent source of physiologic dosages of dehydroepiandrosterone (DHEA).


(Oversættes så snart som muligt, bare ikke i dag. Dødtræt efter 1. omgang af tandkirurgi.)

Kilde:
Sitat Opprinnelig skrevet av Vigdis Vis post
Jeg har ikke lest ferdig boka "Safe uses with cortisol" (har lånt den til min lege). Men legen som har skrevet den har behandlet en rekke sykdommer med hydrokotison i doser som tilsvarer det kroppen lager hver dag (20-40mg). med strålende resultat. Boka fåes ikke kjøpt på Amazon, men fra forrlaget. og den er slett ikke vanskelig å lese, ikke overvettes mye latin! http://www.ccthomas.com/details.cfm?...=9780398075002

Så kanskje kan det være noen svar i den boka? 43 $ i paperback